eLife

Compensation of hyperexcitability with simulation-based inference

Simulation-based inference predicts putative circuit mechanisms of hyperexcitability in a phenomenological microcircuit ...
Science

Graph-based pangenome analysis uncovers structural and functional impacts of allopolyploidization events

The emergence of graph pangenomes has advanced the study of structural variants (SVs) across diverse species, yet the impact of complex ploidy on SV landscapes remains poorly explored. Brettanomyces ...
xenospectrum

ScholarEvolve Lets AI Agents Rewrite Their Own Code From Research Papers, Lifting Task Completion 12.4 Points

UCSB and Microsoft's ScholarEvolve generates code from academic papers to improve an agent's harness without retraining model ...
Science

Cas9 nickase–mediated contraction of CAG/CTG repeats is associated with phenotypic improvements in a Huntington’s disease mouse model

Cas9 nickase contracts CAG/CTG repeats in Huntington’s disease patient–derived medium spiny neurons and in a mouse disease model.
GitHub

ST-Flow: A Hardware Compiler for Automating Spatial-Temporal Dataflow Acceleration

This traces the model, explores the design space, emits an HLS dataflow design in a project directory (here 500_gemm_comb_sa_balanced.prj/) and checks it against PyTorch with C-simulation. The ...